Metabolism of VLDL and LDL subclasses

Abstract
The recognition of lipoprotein heterogeneity has given new depth to our understanding of lipoprotein metabolism and the role of plasma triglyceride as a determinant of lipoprotein subclass distribution and potential atherogenicity. It has also provided insight into the relationship between exogenous and endogenous lipid transport pathways, the roles of endothelial lipases and lipid transfer proteins in the remodelling of lipoproteins, and the link between insulin resistance, lipids and coronary disease.

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