Loss-of-function and Dominant-negative Mechanisms Associated with Hepatocyte Nuclear Factor-1β Mutations in Familial Type 2 Diabetes Mellitus

This publication has 16 references indexed in Scilit:

• Mutation in hepatocyte nuclear factor–1β gene (TCF2) associated with MODY
  Nature Genetics, 1997
• Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)
  Nature, 1996
• A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q
  Nature Genetics, 1995
• Organization of the Human GLUT2 (Pancreatic β-Cell and Hepatocyte) Glucose Transporter Gene
  Diabetes, 1993
• HNF1, a homeoprotein member of the hepatic transcription regulatory network
  BioEssays, 1992
• Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus
  Nature, 1992
• HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro.
  Genes & Development, 1991
• Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q.
  Proceedings of the National Academy of Sciences, 1991
• Scope and Heterogeneous Nature of MODY
  Diabetes Care, 1990
• The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain
  Cell, 1989