INFUSIONS OF hFSH AND hLH IN NORMAL MEN
- 1 January 1976
- journal article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 81 (1) , 225-233
- https://doi.org/10.1530/acta.0.0810225
Abstract
Serial serum assays of immunoreactive FSH before, during and after a 4 h intravenous infusion of human follicle stimulating hormone (hFSH) in five healthy men revealed two disappearance rate constants with corresponding mean half-lives of 2.9 and 50.6 h. The mean distribution spaces calculated for the fast and slow component were 4.36 1 and 75.9 1 respectively. The average value for the metabolic clearance rate was 17.2 ml/min and for the endogenous production rate 50.9 mU/min. Two of the subjects had human luteinizing hormone (hLH) added in the infusions without the FSH kinetics changing.Keywords
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