Profile analysis of chondroitin sulfates in human urine and serum.
- 1 January 1989
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 37 (6) , 1627-1628
- https://doi.org/10.1248/cpb.37.1627
Abstract
A highly sensitive high-performance liquid chromatographic method with fluorometric postcolumn labeling using 2-cyanoacetamide was developed for the profile analysis of chondroitin sulfates (ChS) in normal human urine and serum. Over-sulfated disaccharide units such as di- or trisulfated unsaturated disaccharides in urine were estimated and unsaturated 6-sulfated disaccharide (.DELTA.i-6S) was found as a major component from ChS in urine, although only small amounts of .DELTA.Di-6S from ChS were present in serum.This publication has 7 references indexed in Scilit:
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