Blocked 5′-termini in the fragments of chromosomal DNA produced in cells exposed to the antitumour drug 4′-[(9-acridinyl)-amino]methanesulphon-m-anisidide (mAMSA)
- 1 January 1983
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 11 (12) , 4251-4256
- https://doi.org/10.1093/nar/11.12.4251
Abstract
Comparison of the sensitivity of DNA isolated from untreated and mAMSA-treated PY815 mouse mastocytoma cells to hydrolysis by E.coli 3'-exonuclease III and phage lambda or phage T7 5'-exonucleases show that the fragments of chromosomal DNA produced by mAMSA treatment have free 3'-OH termini and blocked 5'-termini.Keywords
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