Cortical Blindness After Metrizamide Myelography
- 1 February 1984
- journal article
- case report
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 41 (2) , 224-226
- https://doi.org/10.1001/archneur.1984.04050140126042
Abstract
• Metrizamide, a nonionic, water-soluble contrast medium, has been increasingly used for myelography. We saw a patient with cortical blindness, seizure, organic psychosis, and asterixis after undergoing attempted metrizamide myelography via C1-2 puncture. Computed tomography demonstrated early penetrance of metrizamide into the brain parenchyma, most prominently in the occipital lobes. A mechanism of direct metrizamide neurotoxicity was proposed.Keywords
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