Towards a Quantitative Model of Immunogenicity: Counting Pathways in Sequence Space
- 21 September 2000
- journal article
- Published by Elsevier in Journal of Theoretical Biology
- Vol. 206 (2) , 255-278
- https://doi.org/10.1006/jtbi.2000.2122
Abstract
No abstract availableKeywords
This publication has 60 references indexed in Scilit:
- Towards a general theory of adaptive walks on rugged landscapesPublished by Elsevier ,2006
- Modelling Evolving PopulationsJournal of Theoretical Biology, 1997
- Isolation of Picomolar Affinity Anti-c-erbB-2 Single-chain Fv by Molecular Evolution of the Complementarity Determining Regions in the Center of the Antibody Binding SiteJournal of Molecular Biology, 1996
- Peptide Libraries Define the Fine Specificity of Anti-polysaccharide Antibodies toCryptococcus neoformansJournal of Molecular Biology, 1996
- CDR Walking Mutagenesis for the Affinity Maturation of a Potent Human Anti-HIV-1 Antibody into the Picomolar RangeJournal of Molecular Biology, 1995
- Somatic Hypermutation in B Cells: An Optimal Control TreatmentJournal of Theoretical Biology, 1993
- Phage antibodies: filamentous phage displaying antibody variable domainsNature, 1990
- The use of markov chain models in studying the evolution of the proteinsJournal of Theoretical Biology, 1988
- Theoretical studies of clonal selection: Minimal antibody repertoire size and reliability of self-non-self discriminationJournal of Theoretical Biology, 1979
- Natural Selection and the Concept of a Protein SpaceNature, 1970