Native Functions of the Androgen Receptor Are Essential to Pathogenesis in a Drosophila Model of Spinobulbar Muscular Atrophy
- 1 September 2010
- Vol. 67 (6) , 936-952
- https://doi.org/10.1016/j.neuron.2010.08.034
Abstract
No abstract availableKeywords
Funding Information
- Kennedy's Disease Association
- Muscular Dystrophy Association
- National Institutes of Health (NS053825)
- American Lebanese Syrian Associated Charities
This publication has 77 references indexed in Scilit:
- TDP-43 Mediates Degeneration in a NovelDrosophilaModel of Disease Caused by Mutations in VCP/p97Journal of Neuroscience, 2010
- Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophyHuman Molecular Genetics, 2009
- Aberrant E2F activation by polyglutamine expansion of androgen receptor in SBMA neurotoxicityProceedings of the National Academy of Sciences, 2009
- Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexesThe EMBO Journal, 2008
- Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1Nature, 2008
- Overexpression of wild-type androgen receptor in muscle recapitulates polyglutamine diseaseProceedings of the National Academy of Sciences, 2007
- HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPSNature, 2007
- Compartmentalization of androgen receptor protein–protein interactions in living cellsThe Journal of cell biology, 2007
- Glutamine-Expanded Ataxin-7 Alters TFTC/STAGA Recruitment and Chromatin Structure Leading to Photoreceptor DysfunctionPLoS Biology, 2006
- The AXH Domain of Ataxin-1 Mediates Neurodegeneration through Its Interaction with Gfi-1/Senseless ProteinsCell, 2005