The first biomimetic conversion of a germacrolide-4-epoxide into a xanthanolide

Abstract
Boron trifluoride catalysed cyclization of the germacrolide-4-epoxide dihydroparthenolide (1) provided two known guaianolides and the xanthanolide (4), the latter transformation representing the first biomimetic conversion of a germacrolide into a xanthanolide.

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