The COOH-terminal domain of hirudin. An exosite-directed competitive inhibitor of the action of alpha-thrombin on fibrinogen.

This publication has 45 references indexed in Scilit:

• Thrombin Anion‐binding Exosite Interactions with Heparin and Various Polyanionsa
  Annals of the New York Academy of Sciences, 1989
• Anion-binding exosite of human .alpha.-thrombin and fibrin(ogen) recognition
  Biochemistry, 1988
• Enzymic properties of proteolytic derivatives of human .alpha.-thrombin
  Biochemistry, 1988
• Catalytic competence of human .alpha.- and .gamma.-thrombin in the activation of fibrinogen and factor XIII
  Biochemistry, 1987
• Effect of heparin on the interaction between thrombin and hirudin
  European Journal of Biochemistry, 1987
• Identification of regions of .alpha.-thrombin involved in its interaction with hirudin
  Biochemistry, 1987
• Multiple complexes of thrombin and heparin
  Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1986
• Human .alpha.-thrombin binding to nonpolymerized fibrin-sepharose: evidence for an anionic binding region
  Biochemistry, 1985
• Solution composition dependent variation in extinction coefficients for p-Nitroaniline
  Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1983
• Slow, spontaneous dissociation of the antithrombin—thrombin complex produces a proteolytically modified form of the inhibitor
  FEBS Letters, 1980