Vertebrate Muscle Fiber Types and Neuronal Regulation of Myosin Expression
Open Access
- 1 November 1987
- journal article
- Published by Oxford University Press (OUP) in American Zoologist
- Vol. 27 (4) , 1033-1042
- https://doi.org/10.1093/icb/27.4.1033
Abstract
SYNOPSIS. Vertebrate skeletal muscles consist of mixtures of different fibers that can be identified by their selective response to antibodies against fast or slow myosins. At least three developmental forms of myosin are expressed sequentially during normal differentiation. Alteration of the nerve supply by neuromuscular block or by cross-reinnervation can effect a conversion of the myosin pattern, and in some cases, a new myosin is synthesized that is not normally present. Muscle fiber composition is therefore influenced by the type of nerve supply, but the type of myosin is not specified by the motoneuron alone.Keywords
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