Reaktionen von Uracilen; 151,2,3. 7-Ethoxypyrimido[4,5-d] pyrimidine über ein Uracil-carbodiimid-Derivat und deren Aminolyse- und Pyrolyse-Folgeprodukte
- 1 January 1988
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1988 (11) , 919-921
- https://doi.org/10.1055/s-1988-27756
Abstract
Reactions of Uracils; 15.1,2,3 7-Ethoxypyrimido[4,5-d] pyrimidines via a Uracil-Carbodiimide Derivative and Their Products of Aminolysis and Pyrolysis Ethyl 1,3-dimethyl-6-(triphenylphosphoranylideneamino)uracil-5-carboxylate (2) reacts with isocyanates via a uracil-carbodiimide derivative to afford a new approach to 7-ethoxypyrimido[4,5-d]pyrimidines 3a-f. The aminolysis of 3a, b gives the substituted 7-aminopyrimido[4,5-d] pyrimidines 4a-c, whereas the pyrolysis of 3a gives 2,4,5,7-tetraoxo-1,2,3,4,5,6,7,8-octahydropyrimido [4,5-d]pyrimidine 5 by syn-elimination.Keywords
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