Abstract
Two human cases in which gastrointestinal bleeding was localized by serial scintigraphic imaging with red blood cells labeled in vivo with 99mTc-PYP [99mTc-pyrophosphate] are reported. The importance of both early serial imaging and delayed imaging and of the correlation with other radiographic techniques is demonstrated. Reflux of blood from the sigmoid into the proximal colon was observed in both cases. In 1 case, contrast material injected into a resected specimen confirmed the scintigraphic localization of the site of bleeding.