Isolation and characterization of a glycoprotein from human colostrum
- 1 December 1973
- journal article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 135 (4) , 875-880
- https://doi.org/10.1042/bj1350875
Abstract
A glycoprotein was isolated from the M-1 acid glycoprotein fraction of human colostrum. It had a molecular weight of 31200 and contained 27% galactose, 21.7% hexosamine, 8.0% fucose and 10.8% sialic acid by weight. The glycoprotein had no absorption maxima in the 240–300nm region, and was virtually free of ABH(O) and M and N blood-group activity. Alkaline borohydride cleavage of the glycoprotein resulted predominantly in the destruction of threonine and galactosamine.Keywords
This publication has 21 references indexed in Scilit:
- Pentose-rich glycoprotein from bovine vitreous body I. Isolation and partial characterizationBiochimica et Biophysica Acta (BBA) - General Subjects, 1973
- Determination of hexosaminitols by ion-exchange chromatography and its application to alkali-labile glycosidic linkages in glycoproteinsArchives of Biochemistry and Biophysics, 1969
- Ultracentrifugal behavior of transferrin in the presence of some anionsBiochimica et Biophysica Acta (BBA) - Biophysics including Photosynthesis, 1966
- Isolation and Properties of Human Blood-Group NN and Meconium-Vg Antigens*Biochemistry, 1966
- A rapid procedure for the estimation of amino sugars on a micro scaleAnalytical Biochemistry, 1966
- Comparative study of the acid glycoproteins isolated from bovine serum, colostrum, and milk wheyArchives of Biochemistry and Biophysics, 1965
- DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*Annals of the New York Academy of Sciences, 1964
- Colostrum humain. Chromatographie sur deae-cellulose de la fraction glycopeptidique soluble dans l'éthanol à 50%Biochimica et Biophysica Acta, 1963
- Bifidus factor. II. Its occurrence in milk from different species and in other natural productsArchives of Biochemistry and Biophysics, 1954
- Bifidus factor. I. A variant of Lactobacillus bifidus requiring a special growth factorArchives of Biochemistry and Biophysics, 1954