ROENTGEN-RAY THERAPY OF THE HYPOPHYSIS IN A PATIENT WITH ACROMEGALY

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Abstract
The widespread involvement of various organs and tissues of the body in that remarkable disease, acromegaly, has been commented on by many writers. In a monograph detailing the autopsies in four cases, Cushing and Davidoff1emphasized the protean manifestations produced by the exaggerated secretion from the anterior portion of the hypophysis. They called attention not only to the extraordinary osseous deformities and "acromegalic myxedema" which hitherto have dominated the clinical picture but also to the pronounced visceromegalies (cardiac, hepatic, renal, splenic, etc.), and to the noteworthy secondary involvement of most of the other ductless glands. Several publications of late have dealt particularly with the carbohydrate metabolism in acromegaly (for instance, those of Cushing and Davidoff,2Colwell,3John4and Ellis5). The incidence of diabetes mellitus in acromegaly has been variously estimated from 9 per cent (Arnold6) to as high as 40 per cent (Borchardt7). Cushing and Davidoff2reported glycosurhi one out

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