[Correlation between the loss of plasmid DNA and the transition from virulent phase I to avirulent phase II in Shigella sonnei].

  • 31 March 1980
    • journal article
    • abstracts
    • Vol. 290  (13) , 879-82
Abstract
Transition from virulent phase I to non virulent phase II in five strains of Shigella sonnei was studied by immunofluorescence and plasmid electrophoresis. High frequency loss of phase I specific antigens was observed by use of fluorescent phase specific antibodies. Agarose gel electrophoresis of bacterial lysates showed that transition from phase I to phase II is associated with the loss of extrachromosomal DNA.

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