Characterization of plasmids conferring resistance to gentamicin and apramycin in strains ofSalmonella typhimuriumphage type 204c isolated in Britain

Publisher Website
Google Scholar
Abstract
SUMMARY: InSalmonella typhimuriumphage type 204c isolated in Britain, gentamicin resistance is specified by plasmids of the I1compatibility group which also confer resistance to apramycin. These plasmids have been subdivided into three types within the I1group on the basis of their antibiotic resistance specificity, their ability to produce colicin Ib and their restriction enzyme digest fragmentation patterns. All three have been identified in strains from cattle, but as yet only two types have been found in strains from humans.It is suggested that the use of apramyein in animal husbandry is responsible for the appearance of gentamicin resistance in multiresistant strains of phage type 204 c, a phage type already epidemic in bovine animals and with an increasing incidence in humans.