Viral Infections and Local IgA

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Abstract
Many investigations of viral infection have attempted in recent years to define both the host factors involved in the initial recovery process and the elements responsible for the prevention of later reinfection. Information has accumulated that permits the identification of a number of diverse proteins of considerable importance to these two defense mechanisms. During the acute infection, interferon, a low-molecular-weight protein, apparently plays a key part in the limitation of virus replication within cells already infected and in the protection of nearby and distant cells from the spread of infection. From blood and other body fluids various globulins have been . . .