Variations in responses to non‐steroidal anti‐inflammatory drugs.
Open Access
- 1 November 1982
- journal article
- research article
- Published by Wiley in British Journal of Clinical Pharmacology
- Vol. 14 (5) , 691-694
- https://doi.org/10.1111/j.1365-2125.1982.tb04958.x
Abstract
1 This paper assesses the variability in the response of patients with rheumatoid disease to a group of non‐steroidal anti‐inflammatory drugs (NSAID). 2 Thirty six patients were divided into three groups and each group received a set of four NSAID. The different drugs were each given three times daily for a week and the treatment order was randomised. 3 The study demonstrated marked variability and unpredictability in patient responses and cast doubt on the value of comparative trials of different NSAID.This publication has 6 references indexed in Scilit:
- Sulindac. Trials of a new anti-inflammatory drug.Annals of the Rheumatic Diseases, 1978
- New nonsteroidal anti-inflammatory drugs. Prospective survey of relative merits.1977
- Four new anti-inflammatory drugs: responses and variations.BMJ, 1976
- Long-term study of indomethacin and alclofenac in treatment of rheumatoid arthritis.BMJ, 1975
- Charts of the power function for analysis of variance tests, derived from the non-central F-distribution.1951
- CHARTS OF THE POWER FUNCTION FOR ANALYSIS OF VARIANCE TESTS, DERIVED FROM THE NON-CENTRAL F-DISTRIBUTIONBiometrika, 1951