ACANTHOSIS NIGRICANS: JUVENILE TYPE
- 11 December 1926
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 87 (24) , 1964-1969
- https://doi.org/10.1001/jama.1926.02680240008003
Abstract
Since the original communications by Pollitzer 1 and Janovsky 2 concerning acanthosis nigricans, reports of about ninety-five authentic cases have been collected from various sources, these embodying two types of the disease. One, the larger group, has shown a striking association with malignant disease, chiefly of the abdominal viscera; and because of this, together with the unfavorable prognosis for life in this class of cases, it has been termed the malignant type of the disease. The smaller group includes those cases in which there is neither evidence of malignant change nor marked impairment of the general health. This is known as the benign type; and although it may occur in older persons, it usually is found in the first two decades of life. As early as 1893, Hallopeau 3 called attention to the association with malignant disease, and suggested an analogy between the cutaneous changes and the coincident neoplastic changesThis publication has 0 references indexed in Scilit: