Total synthesis of the macrocyclic antibiotic (±)-pyrenophorin
- 1 January 1976
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 16,p. 1718-1722
- https://doi.org/10.1039/p19760001718
Abstract
The total synthesis of the macrocyclic antibiotic pyrenophorin (8,16-dimethyl-1,9-dioxacyclohexadeca-3,11-diene-2,5,10,13-tetraone)(16) is described, involving the use of the 2-(p-tolylsulphonyl)ethyl ester as a selectively removable protecting group for the carboxy-function, and di-imidazol-1-yl ketone as a lactonising reagent.Keywords
This publication has 1 reference indexed in Scilit:
- Total synthesis of the macrolide, zearalenoneTetrahedron, 1968