High-Resolution Sonography in Experimentally Induced Scrotal Pathology

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Abstract
Benign and malignant extra- and intratesticular lesions were experimentally induced in the testes of Wistar rats so as to evaluate the significance of high-resolution ultrasonography for the early detection of intratesticular malignancy. The animals were studied using high-resolution sonography (mean frequency = 8 MHz) > 6 wk. Walker carcinomas could be induced in the testicle in 50% of the cases; 8 of 17 showed a locally limited growth. Tumors > 2 mm in diameter showed a typical change in the normal sonographic pattern of the testes. The overall sensitivity of high-resolution sonography of intratesticular lesions was 88%, the specificity 91%. The detection of small intratesticular lesions had made high-resolution sonography superior to conventional sonographic techniques and may prove to be of major clinical significance [in humans].

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