MODIFICATION OF CHROMATIDS BEFORE FIXATION - PRODUCTION OF G-BANDS WITH CERTAIN STAINS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 19  (3) , 217-218
Abstract
Acridine orange, coriphosphine, toludine blue, or pyronine, when added to the hypotonic solution, allow G-banding when the fixed slides are stained in the usual way. Apart from this simple practical application, these modifications of chromatid structure by a treatment applied before fixation shed some light on the molecular mechanisms responsible for [human] chromosome banding.

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