Similarity of secretory protein I from parathyroid gland to chromogranin A from adrenal medulla.
- 1 October 1982
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 79 (19) , 6056-6059
- https://doi.org/10.1073/pnas.79.19.6056
Abstract
The amino acid and carbohydrate compositions, partial amino acid sequences, immunological crossreactivity and physical properties of secretory protein I of the [bovine] parathyroid gland and chromogranin A of adrenal gland were compared. This comparison indicates that these proteins are similar molecules. Because secretory protein I is present in secretory granules containing parathormone and is cosecreted with the hormone, and because chromogranin A is contained within chromaffin granules and is secreted with the catecholamines, the present observations raise the possibility that this class of protein plays a general role in hormone secretion or storage mechanisms.This publication has 30 references indexed in Scilit:
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