Replication of Borna disease virus in cell cultures
- 1 July 1980
- journal article
- research article
- Published by Springer Nature in Medical Microbiology and Immunology
- Vol. 168 (3) , 153-158
- https://doi.org/10.1007/bf02122849
Abstract
Borna disease (BD) virus from infected brain tissue of horses or rabbits could be grown in embryonic brain cells from rabbits or rats with high virus yields. The cells became persistently infected and could be subcultivated without loss of infectivity. Cocultivation of infected rabbit brain (ERB) cells with GMK-, Vero-, or MDCK-cells led to persistently infected cell lines. BD virus grown in MDCK cells after cocultivation became adapted to this cell type and could be used directly for further infection of MDCK cells.This publication has 4 references indexed in Scilit:
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