Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?

This publication has 42 references indexed in Scilit:

• PREDICTION OF PLASMODIUM FALCIPARUM RESISTANCE TO SULFADOXINE/ PYRIMETHAMINE IN VIVO BY MUTATIONS IN THE DIHYDROFOLATE REDUCTASE AND DIHYDROPTEROATE SYNTHETASE GENES: A COMPARATIVE STUDY BETWEEN SITES OF DIFFERING ENDEMICITY
  The American Journal of Tropical Medicine and Hygiene, 2003
• Persistence of antibiotic resistant bacteria
  Current Opinion in Microbiology, 2003
• INCREASING PREVALENCE OF WILDTYPES IN THE DIHYDROFOLATE REDUCTASE GENE OF PLASMODIUM FALCIPARUM IN AN AREA WITH HIGH LEVELS OF SULFADOXINE/PYRIMETHAMINE RESISTANCE AFTER INTRODUCTION OF TREATED BED NETS
  The American Journal of Tropical Medicine and Hygiene, 2003
• The puzzling links between malaria transmission and drug resistance
  Trends in Parasitology, 2003
• High prevalence of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in Malawi
  Acta Tropica, 2003
• The cost of antibiotic resistance from a bacterial perspective
  Drug Resistance Updates, 2000
• Effects of Environment on Compensatory Mutations to Ameliorate Costs of Antibiotic Resistance
  Science, 2000
• The biological cost of antibiotic resistance
  Published by Elsevier ,1999
• Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria
  Antimicrobial Agents and Chemotherapy, 1997
• Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from Subsaharan Africa
  Molecular and Biochemical Parasitology, 1995