IS NONSPECIFIC CROSS-REACTING ANTIGEN A MARKER ON SURFACE OF HUMAN BASOPHILS

  • 1 January 1977
    • journal article
    • research article
    • Vol. C128  (6) , 979-984
Abstract
Leukocytes challenged with anti-NCA serum (non-specific cross-reacting antigen) can release histamine. This release is Ca2+, glucose and temperature dependent as usually described for basophils. Only half of the subjects whose basophils can release histamine when challenged with anti-Ig[immunoglobulin]E serum are also able to release histamine with anti-NCA serum. There is no cross-reaction between IgE and anti-NCA serum or between NCA and anti-IgE serum. NCA may be a marker on the surface of some human basophils.

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