2-Phenoxyethanol as a General Anaesthetic for Sockeye Salmon
- 1 June 1963
- journal article
- research article
- Published by Canadian Science Publishing in Journal of the Fisheries Research Board of Canada
- Vol. 20 (6) , 1435-1440
- https://doi.org/10.1139/f63-097
Abstract
The dose-response relationship of 2-phenoxyethanol, as a general anaesthetic, in adult sockeye salmon (Oncorhynchus nerka) has been investigated. At 11[degree]C the effective dose (ED50) and lethal dose (LD50) were approximately 43 and 130 ml/100 Imperial gal, respectively. The (LD50) therapeutic ratio [image] was more than 3, indicating a good margin of safety. At a lowered aquarium temperature of 4[degree]C the anaesthetic effects of 2-phenoxyethanol were potentiated. ED50 and LD50 at this temperature were approximately 25 and 130 ml/100 gal of water, respectively. The therapeutic ratio was more than 5, indicating that the margin of safety was increased by the decrease in temperature.This publication has 4 references indexed in Scilit:
- Resumption of Feeding by and Survival of Adult Sockeye Salmon (Oncorhynchus nerka) Following Advanced Gonad DevelopmentJournal of the Fisheries Research Board of Canada, 1963
- OLFACTORY PERCEPTION IN MIGRATING SALMON: II. STUDIES ON A LABORATORY BIO-ASSAY FOR HOMESTREAM WATER AND MAMMALIAN REPELLENTCanadian Journal of Biochemistry and Physiology, 1961
- Temperature Tolerance in Young Pacific Salmon, Genus OncorhynchusJournal of the Fisheries Research Board of Canada, 1952
- RELATIONS BETWEEN AGE AND WEIGHT AND DOSAGE OF DRUGSAnnals of Internal Medicine, 1940