Hydrogel keratophakia: a microkeratome dissection in the monkey model.
Open Access
- 1 March 1986
- journal article
- research article
- Published by BMJ in British Journal of Ophthalmology
- Vol. 70 (3) , 192-198
- https://doi.org/10.1136/bjo.70.3.192
Abstract
High water content intracorneal implants were fabricated from Vistamarc hydrogel (Vistakon, Inc.) at 58%, 68%, and 72% water content and a range of powers from +7.25 to +17.00 dioptres. The Barraquer microkeratome technique was used to implant the lens at 59.0 +/- 9% (+/- SD) depth in the corneas of 14 rhesus monkey eyes. The contralateral eye served as a control. Three eyes were lost to the study because of complications. The remaining 11 animals were followed up for 51 +/- 2 weeks with the refractive yield being 118 +/- 34% and the keratometric yield being 92 +/- 30%. The measured and theoretically expected refractive changes have a linear regression line correlation coefficient of 0.74, whereas the respective keratometric data had a correlation coefficient of 0.04. The measured refraction became stable within 2 to 3 dioptres after 20 postoperative weeks. The hydrogels were well tolerated within the corneal tissue. There was a minimum of interface problems except along the edge of the implant. Implants with abruptly cut edges versus a fine wedge tended to have more light scattering collagen at the implant margin.This publication has 4 references indexed in Scilit:
- Hydrogel keratophakia: a freehand pocket dissection in the monkey model.British Journal of Ophthalmology, 1986
- Predicting refractive alterations with hydrogel keratophakia.1985
- Hydrophilic lenses for refractive keratoplasty: the use of factory lathed materials.1984
- REFRACTIVE KERATOPLASTY WITH INTRA-STROMAL HYDROGEL LENTICULAR IMPLANTS1981