Obstructed Axoplasmic Transport in Purtscher’s Traumatic Retinopathy

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Abstract
Two patients with unilateral traumatic Purtscher''s retinopathy are reported. The postraumatic increase of the cephalic venous pressure may cause subconjunctival hemorrhages and retinal venous stasis followed by hemorrhages and ischemic changes, e.g., capillary nonperfusion and cotton-wool spots. Correlation of the fundus picture with fluorescein angiograms implies the cotton-wool spots found in association with capillary non-perfusion result from the obstruction of the orthograde and the retrograde axonal flow in the retinal ganglion cell axons. After recovery, funduscopic and perimetric evidence of nerve fiber bundle defect was found.

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