Trypanosoma congolense: Partial Cyclic Development in a Glossina Cell System and Oxygen Consumption

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Abstract
An established Glossina cell line with a modified insect tissue culture medium supports transformation of bloodstream forms and continuous growth of procyclic forms of T. congolense. Midmastigotes differentiate reproducibly to epimastigotes, but metacyclic forms are not produced, as shown by the absence of infectivity to mice and rats. Cultivation of T. congolense may require vector-specific factors, since Drosophilia cells do not support growth. The respiration/inhibition pattern of T. congolense bloodstream and procyclic forms closely resembles that of T. brucei, except for the absence of an initial cyanide-insensitive phase in established culture forms.