A model of the breakdown and removal of the chromatin components during Feulgen acid hydrolysis
- 1 July 1976
- journal article
- research article
- Published by Springer Nature in Journal of Molecular Histology
- Vol. 8 (4) , 419-430
- https://doi.org/10.1007/bf01003830
Abstract
Synopsis A stochastic model of Feulgen hydrolysis is proposed. The model, constructed so as to embody the main features of chromatin structure, is simple enough to allow the calculation of extraction rates. Extraction rate curves generated by the model are compared with experimental curves obtained under various conditions (different fixatives and hydrolysis solutions). A good correspondence is found between the experiments and the predictions of the model.Keywords
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