Skin score: A semiquantitative measure of cutaneous involvement that improves prediction of prognosis in systemic sclerosis

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Abstract
Cutaneous sclerosis, assessed yearly by a semiquantitative skin scoring technique (sum of 10 body areas, each scored on a scale of 0–3 for tethering, by clinical palpation), and outcome at 10 years were evaluated in 90 systemic sclerosis patients enrolled in a 3‐year, prospective drug trial. The inverse relationship of survival to the skin score at study entry (increasing skin score associated with decreasing survival) (P < 0.003) was more significant than was the relationship found by using classification schemata that rely only on distribution of cutaneous sclerosis. Six‐year survival was 40% in patients with entry skin scores ≥15 and 73% when skin scores were P < 0.005). An entry skin score ≥15 was associated with a high risk of early fatal renal and cardiac complications.