Increased aquaporin 1 water channel expression inhuman brain tumours
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Open Access
- 3 September 2002
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 87 (6) , 621-623
- https://doi.org/10.1038/sj.bjc.6600512
Abstract
Aquaporin 1 is a water channel protein. There was little aquaporin 1 immunoreactivity in normal brain parenchyma. In astrocytomas, aquaporin 1 was expressed in microvessel endothelia and neoplastic astrocytes. In metastatic carcinomas, aquaporin 1 was present in microvessel endothelia and reactive astrocytes. Aquaporin 1 may participate in the formation of brain tumour oedema.Keywords
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