Deep brain stimulation in myoclonus–dystonia syndrome
- 12 February 2004
- journal article
- case report
- Published by Wiley in Movement Disorders
- Vol. 19 (6) , 724-727
- https://doi.org/10.1002/mds.20030
Abstract
Myoclonus–dystonia syndrome (MDS) is an autosomal dominant disorder characterized by bilateral myoclonic jerks. An 8‐year‐old boy presenting with early onset, medically intractable, MDS due to a mutation in the ϵ‐sarcoglycan gene (SGCE) underwent chronic bilateral stimulation of the globus pallidus internus, which eliminates both myoclonus and dystonia. We conclude that deep brain stimulation can be an effective and safe treatment for MDS. © 2004 Movement Disorder SocietyKeywords
This publication has 24 references indexed in Scilit:
- Evidence That Paternal Expression of the ε-Sarcoglycan Gene Accounts for Reduced Penetrance in Myoclonus-DystoniaAmerican Journal of Human Genetics, 2002
- ε‐sarcoglycan mutations found in combination with other dystonia gene mutationsAnnals of Neurology, 2002
- Myoclonus–dystonia syndrome: ε‐sarcoglycan mutations and phenotypeAnnals of Neurology, 2002
- Comparison of atlas- and magnetic resonance imaging—based stereotactic targeting of the globus pallidus internus in the performance of deep brain stimulation for the treatment of dystoniaJournal of Neurosurgery, 2002
- Deep Brain Stimulation for DystoniaStereotactic and Functional Neurosurgery, 2002
- Magnetic resonance imaging stereotactic target localization for deep brain stimulation in dystonic childrenJournal of Neurosurgery, 2000
- Pallidal stimulation for generalized dystoniaJournal of Neurosurgery, 2000
- Pallidal stimulation: an alternative to pallidotomy?Journal of Neurosurgery, 1997
- The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding proteinNature Genetics, 1997
- Stereotaxis and nuclear magnetic resonance.Journal of Neurology, Neurosurgery & Psychiatry, 1985