Urinary Excretion of Amino Acids by the Rat.

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Abstract
Rats were fed diets deficient in tryptophane, ribo-flavin, or nicotinic acid and the amts. of microbiologically available histidine, arginine, threonine, phenylalanine and tryptophane excreted in the urine were detd. No large changes were noted in the amts. of these amino acids excreted in the urine when rations deficient in nicotinic acid were fed. Rats fed a riboflavin or a tryptophane deficient diet excreted approx. twice as much of the ingested amino acids as animals fed adequately supplemented diets. In all cases, however, the amts. excreted were small, less than 2.5% of those ingested. After acid hydrolysis of the urine samples, a 2-4 fold increase was observed in the values for histidine, arginine, threonine, and phenylalanine.