INFLUENCE OF BODY WEIGHT ON ESTRADIOL METABOLISM IN YOUNG WOMEN

1 November 1975

journal article
research article
Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism

Vol. 41 (5) , 989-991
https://doi.org/10.1210/jcem-41-5-989

Abstract

The metabolism of estradiol in girls with anorexia nervosa was compared with obese subjects and normal weight, age and sex matched controls. Increasing body weight was accompanied by a sharp decrease in 2-hydroxylation of estradiol and an increase in 16alpha-hydroxylation. These metabolic changes are discussed in terms of the biological activity of 2-hydroxyestrone and estriol.

Keywords

BODY WEIGHT