Case 11-1982

Abstract
Presentation of CaseA 29-year-old man was admitted to the hospital because of chronic urticaria, proteinuria, and cryoglobulinemia.He was well until five years earlier, when episodes of diffuse urticaria developed, sometimes accompanied by edema of the tongue, lips, periorbital areas, and extremities. Most of the episodes were spontaneous, although some were precipitated by the ingestion of aspirin. Some of them were accompanied by dyspnea, without wheezing. An antihistamine provided relief of symptoms. During the year before admission he experienced increased fatigue, and for several months he observed Raynaud's phenomenon. Three months before entry he felt a firm nodule in . . .