Electronic measurement of red cell flow in micropipettes

Publisher Website
Google Scholar
Abstract
The velocity of human erythrocytes in flow-through tubes of diameter less than 5 μm is measured as a function of driving pressure. The electrical resistance in the lumen of the tube increases when a cell is present, so a pulse can be generated of length inversely proportional to velocity. In the apparatus described the pulses and driving pressure are fed to a computer which derives the correlation between pressure and velocity. Experiments confirm that the resistance to flow of erythrocytes in a narrow tube is substantially the same as that of the suspending medium. The apparatus is being used to study the effects of changes in erythrocyte deformability on flow.

This publication has 0 references indexed in Scilit: