Valproate-induced hyperammonaemia in two epileptic identical twins
- 1 July 1985
- journal article
- case report
- Published by Springer Nature in Zeitschrift für Neurologie
- Vol. 232 (3) , 167-168
- https://doi.org/10.1007/bf00313894
Abstract
The cases of two epileptic identical twins are described, one of whom had presented an episode of valproate (VPA)-induced stupor associated with very high blood ammonia (NH3) concentrations. Both twins showed a similar marked increase of venous NH3 concentrations after the administration of a single loading dose of VPA (800 mg).Keywords
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