Thyroglobulin in cord blood

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Abstract
The cord thyroglobulin (Tg) concentration was estimated in 160 full-term newborns of whom 103 were delivered normally, 26 by elective Ceasarean section and 31 by vacuum extraction. There was no correlation between the median cord Tg concentration and gestational age at delivery (37–43 weeks), birth weight or sex of the child or the median cord TSH concentration. The median cord Tg concentration was significantly higher in the children born by Ceasarean section than in those delivered by vacuum extraction (PP<0.001), whereas the median cord TSH concentration did not differ between these groups. It therefore seems possible that components of cigarette smoke, e.g. thiocyanate, may have a direct effect on the thyroid gland of the fetus.