PHYSIOLOGICAL METHODS IN THE DIAGNOSIS AND TREATMENT OF ASTHMA AND EMPHYSEMA
- 1 October 1938
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 12 (4) , 454-481
- https://doi.org/10.7326/0003-4819-12-4-454
Abstract
Graphic recording of pulmonary ventilation is employed as a quantitative and qualitative test of respiratory function in patients with asthma and pulmonary emphysema by use of a Benedict-Roth basal metabolism apparatus using various gases for testing. An 80% helium and 20% O2 mixture may compensate for a 50% reduction in normal diam. of the larynx or trachea; a lessened reduction in use of bronchial tree e.g., status asthmaticus. The use of 1-100 adrenalin or 1% neo-synephrin often terminates attacks of asthma. 40-50% conc. of O2 for prolonged periods is found useful in treating continuous asthmatic dyspnoea, and pulmonary emphysema: this results in an initial rise in CO2 content of arterial blood followed by a substantial lowering. Detailed directions as to the use of O2 therapy as well as the helium-oxygen mixture are given.Keywords
This publication has 5 references indexed in Scilit:
- AN ARTICLE CONTRIBUTED TO AN ANNIVERSARY VOLUME IN HONOR OF DOCTOR JOSEPH HERSEY PRATTAnnals of Internal Medicine, 1938
- THE EFFECTS OF INHALATION OF HELIUM MIXED WITH OXYGEN ON THE MECHANICS OF RESPIRATION 1Journal of Clinical Investigation, 1936
- THE USE OF HELIUM IN THE TREATMENT OF ASTHMA AND OBSTRUCTIVE LESIONS IN THE LARYNX AND TRACHEAAnnals of Internal Medicine, 1935
- THE ELASTIC PROPERTIES OF THE EMPHYSEMATOUS LUNG AND THEIR CLINICAL SIGNIFICANCE 1Journal of Clinical Investigation, 1934
- A Helmet for Use in Clinical Studies of Gaseous MetabolismNew England Journal of Medicine, 1930