The mniopetals, new inhibitors of reverse transcriptases from a Mniopetalum species (Basidiomycetes). I. Producing organism, fermentation, isolation and biological activities.
- 1 January 1994
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 47 (7) , 733-739
- https://doi.org/10.7164/antibiotics.47.733
Abstract
Six novel enzyme inhibitors of RNA-directed DNA-polymerases of human immunodeficiency-, avian myeloblastosis and murine leukemia viruses were isolated from fermentations of a canadian Mniopetalum species. They were named mniopetals A, B, C, D, E and F. Their structures were elucidated by spectroscopic methods. The compounds, in addition to their inhibitory activities on reverse transcriptases, exhibit antimicrobial and cytotoxic properties.Keywords
This publication has 0 references indexed in Scilit: