IMMUNE STATUS IN UNTREATED CERVICAL-CANCER PATIENTS

  • 1 January 1981
    • journal article
    • research article
    • Vol. 28  (1) , 111-116
Abstract
Eighty untreated cervical carcinoma patients were tested for their immune status by evaluating levels of circulating T and B lymphocytes and lymphocyte reactivity to PHA [phytohemagglutinin]. Significant reduction in T lymphocytes and depressed lymphocyte reactivity to PHA was observed following the progression of the disease. B lymphocyte levels remained unaffected. The general impairment observed in cell-mediated immunity was more pronounced in the disseminated disease than in the localized group.