Inhibition of Neutral Endopeptidase Causes Vasoconstriction of Human Resistance Vessels In Vivo
- 16 June 1998
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Circulation
- Vol. 97 (23) , 2323-2330
- https://doi.org/10.1161/01.cir.97.23.2323
Abstract
Background—Neutral endopeptidase (NEP) degrades vasoactive peptides, including the natriuretic peptides, angiotensin II, and endothelin-1. Systemic inhibition of NEP does not consistently lower blo...Keywords
This publication has 54 references indexed in Scilit:
- Suppression of plasma endothelin-1 level by a α-human atrial natriuretic peptide and angiotensin converting enzyme inhibition in normal menLife Sciences, 1993
- Plasma brain natriuretic peptide and endopeptidase 24.11 inhibition in hypertension.Hypertension, 1993
- Endopeptidase 24.11 inhibition by SCH 42495 in essential hypertension.Hypertension, 1993
- Dietary sodium and inhibition of neutral endopeptidase 24.11 in essential hypertension.Hypertension, 1991
- Phosphoramidon Blocks the Pressor Activity of Big Endothelin[1–39] and Lowers Blood Pressure in Spontaneously Hypertensive RatsJournal of Cardiovascular Pharmacology, 1991
- Enkephalinase (EC 3.4.24.11) inhibitors: Protection of endogenous ANF against inactivation and potential therapeutic applicationsLife Sciences, 1990
- Inhibition of endopeptidase EC 24.11 in humans. Renal and endocrine effects.Hypertension, 1990
- Analysis of serial measurements in medical research.BMJ, 1990
- UK-69, 578, a novel inhibitor of EC 3.4.24.11 which increases endogenous ANF levels and is natriuretic and diureticBiochemical and Biophysical Research Communications, 1989
- A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in ratsLife Sciences, 1981