Prenatal detection of monosomy 21 mosaicism
- 1 March 1993
- journal article
- review article
- Published by Wiley in Prenatal Diagnosis
- Vol. 13 (3) , 163-169
- https://doi.org/10.1002/pd.1970130303
Abstract
We report a case of chromosomal mosaicism for monosomy 21 revealed in amniotic fluid cell culture. Ultrasound examination at 19 weeks' gestation showed in utero growth retardation and a complex cardiac malformation. A repeated amniocentesis confirmed the presence of monosomy 21 mosaicism. In view of the sonographically detected fetal abnormalities, termination of pregnancy was elected.Keywords
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