Ultrasound guided sclerosis of neovessels in painful chronic Achilles tendinosis: pilot study of a new treatment
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Open Access
- 1 June 2002
- journal article
- clinical trial
- Published by BMJ in British Journal of Sports Medicine
- Vol. 36 (3) , 173-175
- https://doi.org/10.1136/bjsm.36.3.173
Abstract
Background: The mechanism that causes pain in chronic Achilles tendinosis is not known. However, high resolution colour Doppler ultrasound has shown that neovascularisation may be involved. Objective: To investigate if sclerosing the neovessels would affect the level of tendon pain. Methods: The effect of colour Doppler ultrasound guided injection of a sclerosing agent, polidocanol, against neovessels was studied in 10 patients (seven men and three women, mean age 55 years) with painful chronic mid-portion Achilles tendinosis. Results: Eight patients were satisfied with the results of treatment. There was significantly reduced pain during activity (reported on a visual analogue scale (VAS)) and no remaining neovascularisation after an average of two injections. Two patients were not satisfied, and neovascularisation remained. At the six month follow up, the same eight patients remained satisfied and could perform Achilles tendon loading activities as desired. Their VAS score had decreased from 74 before treatment to 8 (pConclusions: Sclerosing neovessels appears to be an effective treatment for painful chronic Achilles tendinosis, suggesting that neovessels play a key part in causing chronic tendon pain.Keywords
This publication has 35 references indexed in Scilit:
- Neovascularisation in Achilles tendons with painful tendinosis but not in normal tendons: an ultrasonographic investigationKnee Surgery, Sports Traumatology, Arthroscopy, 2001
- Glutamate NMDAR1 receptors localised to nerves in human Achilles tendons. Implications for treatment?Knee Surgery, Sports Traumatology, Arthroscopy, 2001
- Superior short-term results with eccentric calf muscle training compared to concentric training in a randomized prospective multicenter study on patients with chronic Achilles tendinosisKnee Surgery, Sports Traumatology, Arthroscopy, 2000
- Where is the pain coming from in tendinopathy? It may be biochemical, not only structural, in originBritish Journal of Sports Medicine, 2000
- Sclerotherapy for Treatment of HemangiomasDermatologic Surgery, 2000
- In situ microdialysis in tendon tissue: high levels of glutamate, but not prostaglandin E 2 in chronic Achilles tendon painKnee Surgery, Sports Traumatology, Arthroscopy, 1999
- Tendon pathology in long-standing achillodynia: Biopsy findings in 40 patientsActa Orthopaedica, 1997
- Chronic Achilles tendinopathy. A survey of surgical and histopathologic findings.1995
- The Australian Polidocanol (Aethoxysklerol) StudyDermatologic Surgery, 1995
- Indications for the Sclerosing Agent PolidocanolThe Journal of Dermatologic Surgery and Oncology, 1993