Calcium mobilization from mitochondria in synaptic transmitter release
Open Access
- 10 November 2003
- journal article
- review article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 163 (3) , 441-443
- https://doi.org/10.1083/jcb.200309111
Abstract
Mitochondria can rapidly accumulate and release Ca2+ upon cell stimulation. A paper by Yang and coworkers in this issue reports an unusual form of synaptic potentiation, dependent on Ca2+ release from mitochondria through the Na+/Ca2+ exchanger and triggered by Na+ entry through voltage-gated channels (Yang et al., 2003).Keywords
This publication has 20 references indexed in Scilit:
- Ca2+ influx–independent synaptic potentiation mediated by mitochondrial Na+-Ca2+ exchanger and protein kinase CThe Journal of cell biology, 2003
- Looking forward to seeing calciumNature Reviews Molecular Cell Biology, 2003
- The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 actionThe EMBO Journal, 2001
- Mitochondria as all‐round players of the calcium gameThe Journal of Physiology, 2000
- Active mitochondria surrounding the pancreatic acinar granule region prevent spreading of inositol trisphosphate-evoked local cytosolic Ca2+ signalsThe EMBO Journal, 1999
- Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca 2+ ResponsesScience, 1998
- Dominant Role of Mitochondria in Clearance of Large Ca2+ Loads from Rat Adrenal Chromaffin CellsNeuron, 1996
- Decoding of cytosolic calcium oscillations in the mitochondriaCell, 1995
- Modulation of intramitochondrial free Ca2+ concentration by antagonists of Na+-Ca2+ exchangeTrends in Pharmacological Sciences, 1993
- Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphateNature, 1983