EVIDENCE FOR ONE FUNCTIONAL PHENYLALANYL TRNA BINDING SITE ON THE 30 S RIBOSOMAL SUBUNIT
- 1 February 1969
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 62 (2) , 498-505
- https://doi.org/10.1073/pnas.62.2.498
Abstract
NH 2 terminal analysis of polyphenylalanine formed from 30S subunit-bound 14 C-phenylalanyl-tRNA suggests that there is only one site in a 30S subunit for specific binding of phenylalanyl-tRNA. Assuming that no movement of the bound phenylalanyl-tRNA takes place during association of 30S subunits with 50S ribosomal subunits, the binding site of the 30S ribosomal subunit corresponds to site 2 (—NH 2 side with respect to the growing polypeptide chain) of the two binding sites of 70S ribosomes.Keywords
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