Obesity in Albino Mice Due to Single Injections of Goldthioglucose

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Abstract
Marked weight gains were produced in stock albino mice by single injns. of goldthiogiucose. Analysis of total body lipids, protein, water, and ash showed these wt. gains to be primarily due to an increase in adipose tissue. This obesity occurred in approx. 33% of the survivors of sublethal doses of goldthiogiucose. Except for centrolobular fatty infiltration of the liver in obese animals, no anatomic lesions were found in the other viscera, the brain and the endocrine organs.

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